The Selective HDAC6 Inhibitor ACY-738 Impacts Memory and Disease Regulation in an Animal Model of Multiple Sclerosis
Multiple sclerosis (MS) is a complex disease characterized by autoimmune demyelination and progressive neurodegeneration. Pathogenetic mechanisms of the disease remain largely unknown. Changes in synaptic functions have been reported; however, the significance of such alterations in the disease cour...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2019-06-01
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Series: | Frontiers in Neurology |
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Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2019.00519/full |