A new human adipocyte model with PTEN haploinsufficiency

A new human adipocyte model with PTEN haploinsufficiency

Few human cell strains are suitable and readily available as in vitro adipocyte models. We used resected lipoma tissue from a patient with germline phosphatase and tensin homolog (PTEN) haploinsufficiency to establish a preadipocyte cell strain termed LipPD1 and aimed to characterize cellular functi...

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Bibliographic Details
Main Authors: Franziska Kässner, Anna Kirstein, Norman Händel, Gordian L. Schmid, Kathrin Landgraf, Antje Berthold, Astrid Tannert, Michael Schaefer, Martin Wabitsch, Wieland Kiess, Antje Körner, Antje Garten
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Adipocyte
Subjects:
lipoma
adipocyte differentiation
sgbs
phosphoinositide-3-kinase
akt
cellular life-span
3d culture
phosphatases
Online Access:http://dx.doi.org/10.1080/21623945.2020.1785083

Internet

http://dx.doi.org/10.1080/21623945.2020.1785083

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