Higher mucosal antibody concentrations in women with genital tract inflammation

Abstract Inflammatory cytokines augment humoral responses by stimulating antibody production and inducing class-switching. In women, genital inflammation (GI) significantly modifies HIV risk. However, the impact of GI on mucosal antibodies remains undefined. We investigated the impact of GI, pre-HIV...

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Bibliographic Details
Main Authors: Parveen Sobia, Thevani Pillay, Lenine J. P. Liebenberg, Aida Sivro, Leila E. Mansoor, Farzana Osman, Jo-Ann S. Passmore, Quarraisha Abdool Karim, Salim S. Abdool Karim, Cheryl Baxter, Lyle R. McKinnon, Derseree Archary
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-02954-0