Diet induced mild hypercholesterolemia in pigs: local and systemic inflammation, effects on vascular injury - rescue by high-dose statin treatment.

Diet induced mild hypercholesterolemia in pigs: local and systemic inflammation, effects on vascular injury - rescue by high-dose statin treatment.

<h4>Objective</h4>The aim of the present study was to comprehensively evaluate systemic and local inflammation as well as progression of vascular inflammation in normal and mechanically injured vessels in a large animal model of mild hypercholesterolemia. Our aim was also to test the eff...

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Bibliographic Details
Main Authors: Marco Busnelli, Stefano Manzini, Alberto Froio, Alessia Vargiolu, Maria Grazia Cerrito, Ryszard T Smolenski, Massimo Giunti, Alessandro Cinti, Augusta Zannoni, Biagio Eugenio Leone, Monica Forni, Maria Laura Bacci, Giorgio Maria Biasi, Roberto Giovannoni, Marialuisa Lavitrano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24260430/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24260430/?tool=EBI

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