Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis.

BACKGROUND:Interleukin-8 (IL-8, CXCL8) is a potent chemoattractant for neutrophils and contributes to acute liver inflammation. Much less is known about IL-8 in chronic liver diseases (CLD), but elevated levels were reported from alcoholic and hepatitis C-related CLD. We investigated the regulation...

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Bibliographic Details
Main Authors: Henning W Zimmermann, Sebastian Seidler, Nikolaus Gassler, Jacob Nattermann, Tom Luedde, Christian Trautwein, Frank Tacke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3120868?pdf=render