ASEPTIC: primary antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis—study protocol for an interventional randomised controlled trial

ASEPTIC: primary antibiotic prophylaxis using co-trimoxazole to prevent SpontanEous bacterial PeritoniTIs in Cirrhosis—study protocol for an interventional randomised controlled trial

Abstract Background Bacterial infection is a major cause of mortality in patients with cirrhosis. Spontaneous bacterial peritonitis (SBP) is a serious and common infection in patients with cirrhosis and ascites. Secondary prophylactic antibiotic therapy has been shown to improve outcomes after an ep...

Full description

Bibliographic Details
Main Authors: Dominic Crocombe, Norin Ahmed, Indran Balakrishnan, Ekaterina Bordea, Marisa Chau, Louise China, Lynsey Corless, Victoria Danquah, Hakim-Moulay Dehbi, John F. Dillon, Ewan H. Forrest, Nick Freemantle, David Peter Gear, Coral Hollywood, Rachael Hunter, Tasheeka Jeyapalan, Yiannis Kallis, Stuart McPherson, Iulia Munteanu, Jim Portal, Paul Richardson, Stephen D. Ryder, Amandeep Virk, Gavin Wright, Alastair O’Brien
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Trials
Subjects:
Liver cirrhosis
Ascites
Co-trimoxazole
Infection
Spontaneous bacterial peritonitis
Antimicrobial resistance
Online Access:https://doi.org/10.1186/s13063-022-06727-6

Internet

https://doi.org/10.1186/s13063-022-06727-6

Similar Items