The journey from gene knockout to clinical medicine: telotristat and sotagliflozin

Marc S Rendell1,2 1Association of Diabetes Investigators, Omaha, NE 68131, USA; 2Rose Salter Medical Research Foundation, Newport Coast, CA 92657, USA Abstract: Gene knockout has been a powerful technique to evaluate the physiologic role of selected gene products. Lexicon pioneered high-throughput...

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Bibliographic Details
Main Author: Rendell MS
Format: Article
Language:English
Published: Dove Medical Press 2019-03-01
Series:Drug Design, Development and Therapy
Subjects:
Online Access:https://www.dovepress.com/the-journey-from-gene-knockout-to-clinical-medicine-telotristat-and-so-peer-reviewed-article-DDDT