A requirement for Krüppel Like Factor‐4 in the maintenance of endothelial cell quiescence

A requirement for Krüppel Like Factor‐4 in the maintenance of endothelial cell quiescence

Rationale and Goal: Endothelial cells (ECs) are quiescent and critical for maintaining homeostatic functions of the mature vascular system, while disruption of quiescence is at the heart of endothelial to mesenchymal transition (EndMT) and tumor angiogenesis. Here, we addressed the hypothesis that K...

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Bibliographic Details
Main Authors: Victoria Mastej, Cassondra Axen, Anita Wary, Richard D. Minshall, Kishore K. Wary
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
endothelial cells
EndMT
fibrosis
transcription factor
quiescence
KLF2
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.1003028/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.1003028/full

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