Transgelin exacerbates pulmonary artery smooth muscle cell dysfunction in shunt‐related pulmonary arterial hypertension

Abstract Aims Orchestrating the transition from reversible medial hypertrophy to irreversible plexiform lesions is crucial for pulmonary arterial hypertension related to congenital heart disease (CHD‐PAH). Transgelin is an actin‐binding protein that modulates pulmonary arterial smooth muscle cell (P...

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Main Authors: Jing‐jing Zhou, Jian Yang, Li Li, Rui‐lin Quan, Xiao‐xi Chen, Yu‐ling Qian, Li Huang, Pei‐he Wang, Yue Li, Xian‐min Meng, Xi Chen, Qing Gu, Jian‐Guo He
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:ESC Heart Failure
Subjects:
Online Access:https://doi.org/10.1002/ehf2.14080