IMMUNOPHENOTYPIC PROFILING REVEALS ALTERED EXPRESSION OF PLATELET ACTIVATION MARKERS IN PATIENTS WITH MYELOPROLIFERATIVE NEOPLASMS

Introduction and aims: Myeloproliferative neoplasms (MPN) are hematological diseases associated with the Janus Kinase 2 (JAK2), calreticulin (CALR), and thrombopoetin receptor (MPL) genetic driver mutations. These mutations leads to a constitutive activation of the JAK-STAT pathway and results in th...

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Bibliographic Details
Main Authors: VL Bassan, PC Paolini, LMG Ramos, FR Morais, PVB Palma, LC Palma, PMM Garibaldi, LL Figueired-Pontes, FA Castro
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Hematology, Transfusion and Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2531137923005941