A Novel PAK1–Notch1 Axis Regulates Crypt Homeostasis in Intestinal InflammationSummary

A Novel PAK1–Notch1 Axis Regulates Crypt Homeostasis in Intestinal InflammationSummary

Background & Aims: p21-activated kinase-1 (PAK1) belongs to a family of serine-threonine kinases and contributes to cellular pathways such as nuclear factor-κB (NF-κB), mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT), and Wingless-related in...

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Bibliographic Details
Main Authors: Adrian Frick, Vineeta Khare, Kristine Jimenez, Kyle Dammann, Michaela Lang, Anita Krnjic, Christina Gmainer, Maximilian Baumgartner, Ildiko Mesteri, Christoph Gasche
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
PAK1
Notch1
Stem Cell
Inflammation
Colitis-Associated Cancer
Inflammatory Bowel Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X20301806

Internet

http://www.sciencedirect.com/science/article/pii/S2352345X20301806

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