Racial disparity in tumor microenvironment and distant recurrence in residual breast cancer after neoadjuvant chemotherapy

Abstract Black, compared to white, women with residual estrogen receptor-positive (ER+) breast cancer after neoadjuvant chemotherapy (NAC) have worse distant recurrence-free survival (DRFS). Such racial disparity may be due to difference in density of portals for systemic cancer cell dissemination,...

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Bibliographic Details
Main Authors: Gina Kim, Burcu Karadal-Ferrena, Jiyue Qin, Ved P. Sharma, Isabelle S. Oktay, Yu Lin, Xianjun Ye, Saeed Asiry, Jessica M. Pastoriza, Esther Cheng, Nurfiza Ladak, John S. Condeelis, Esther Adler, Paula S. Ginter, Timothy D’Alfonso, David Entenberg, Xiaonan Xue, Joseph A. Sparano, Maja H. Oktay
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-023-00547-w