How many markers are needed to robustly determine a cell's type?

Summary: Our understanding of cell types has advanced considerably with the publication of single-cell atlases. Marker genes play an essential role for experimental validation and computational analyses such as physiological characterization, annotation, and deconvolution. However, a framework for q...

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Bibliographic Details
Main Authors: Stephan Fischer, Jesse Gillis
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422101261X