Targeting the Hippo Pathway and Cancer through the TEAD Family of Transcription Factors

The Hippo pathway is a critical transcriptional signaling pathway that regulates cell growth, proliferation and organ development. The transcriptional enhanced associate domain (TEAD) protein family consists of four paralogous transcription factors that function to modulate gene expression in respon...

Full description

Bibliographic Details
Main Authors: Jeffrey K. Holden, Christian N. Cunningham
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/3/81