AlignNemo: a local network alignment method to integrate homology and topology.

Local network alignment is an important component of the analysis of protein-protein interaction networks that may lead to the identification of evolutionary related complexes. We present AlignNemo, a new algorithm that, given the networks of two organisms, uncovers subnetworks of proteins that rela...

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Bibliographic Details
Main Authors: Giovanni Ciriello, Marco Mina, Pietro H Guzzi, Mario Cannataro, Concettina Guerra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3373574?pdf=render