Dihydroquinolines, Dihydronaphthyridines and Quinolones by Domino Reactions of Morita-Baylis-Hillman Acetates

Dihydroquinolines, Dihydronaphthyridines and Quinolones by Domino Reactions of Morita-Baylis-Hillman Acetates

An efficient synthetic route to highly substituted dihydroquinolines and dihydronaphthyridines has been developed using a domino reaction of Morita-Baylis-Hillman (MBH) acetates with primary aliphatic and aromatic amines in DMF at 50–90 °C. The MBH substrates incorporate a side chain acetate positio...

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Bibliographic Details
Main Authors: Joel K. Annor-Gyamfi, Ebenezer Ametsetor, Kevin Meraz, Richard A. Bunce
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Molecules
Subjects:
Morita-Baylis-Hillman acetates
primary amines
domino reactions
dihydroquinolines
dihydronaphthyridines
quinolones
Online Access:https://www.mdpi.com/1420-3049/26/4/890

Internet

https://www.mdpi.com/1420-3049/26/4/890

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