Dityrosine cross-linking and its potential roles in Alzheimer’s disease

Oxidative stress is a significant source of damage that accumulates during aging and contributes to Alzheimer’s disease (AD) pathogenesis. Oxidation of proteins can give rise to covalent links between adjacent tyrosines known as dityrosine (DiY) cross-linking, amongst other modifications, and this o...

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Bibliographic Details
Main Authors: Mahmoud B. Maina, Youssra K. Al-Hilaly, Louise C. Serpell
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1132670/full