Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment

Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment

Abstract Introduction The safety of predicting conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) dementia using apolipoprotein E (APOE) genotyping is unknown. Methods We randomized 114 individuals with MCI to receive estimates of 3‐year risk of conversion to AD dementi...

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Bibliographic Details
Main Authors: Kurt D. Christensen, Jason Karlawish, J. Scott Roberts, Wendy R. Uhlmann, Kristin Harkins, Elisabeth M. Wood, Thomas O. Obisesan, Lan Q. Le, L. Adrienne Cupples, Emilie S. Zoltick, Megan S. Johnson, Margaret K. Bradbury, Leo B. Waterston, Clara A. Chen, Sara Feldman, Denise L. Perry, Robert C. Green, for the REVEAL Study Group
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
Alzheimer's disease
anxiety
apolipoprotein E4
cognitive dysfunction
dementia
depression
Online Access:https://doi.org/10.1002/trc2.12002

Internet

https://doi.org/10.1002/trc2.12002

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