Population Pharmacokinetic Study of Benzylpenicillin in Critically Unwell Adults

Population Pharmacokinetic Study of Benzylpenicillin in Critically Unwell Adults

Pharmacokinetics are highly variable in critical illness, and suboptimal antibiotic exposure is associated with treatment failure. Benzylpenicillin is a commonly used beta-lactam antibiotic, and pharmacokinetic data of its use in critically ill adults are lacking. We performed a pharmacokinetic stud...

Full description

Bibliographic Details
Main Authors: Reya V. Shah, Karin Kipper, Emma H. Baker, Charlotte I. S. Barker, Isobel Oldfield, Barbara J. Philips, Atholl Johnston, Jeffrey Lipman, Andrew Rhodes, Marina Basarab, Mike Sharland, Sarraa Almahdi, Rachel M. Wake, Joseph F. Standing, Dagan O. Lonsdale
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Antibiotics
Subjects:
benzylpenicillin
pharmacokinetics
critical illness
beta-lactam
antibiotic
NONMEM
Online Access:https://www.mdpi.com/2079-6382/12/4/643

Internet

https://www.mdpi.com/2079-6382/12/4/643

Similar Items