NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes

NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes

Abstract The NLRP3 (nucleotide-binding oligomerization domain-like receptor [NLR] family pyrin domain-containing 3) inflammasome is a member of the NLR family of innate immune cell sensors. These are crucial regulators of cytokine secretions, which promote ischemic cell death and insulin resistance....

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Bibliographic Details
Main Authors: Pu Hong, Ruo-Nan Gu, Feng-Xian Li, Xiao-Xing Xiong, Wen-Bin Liang, Zhi-Jian You, Hong-Fei Zhang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Neuroinflammation
Subjects:
Inflammation
Apoptosis
Interleukin-1β
Diabetes mellitus
Stroke
Online Access:http://link.springer.com/article/10.1186/s12974-019-1498-0

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http://link.springer.com/article/10.1186/s12974-019-1498-0

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