The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism

The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism

Ki-67 and RepoMan have key roles during mitotic exit. Previously, we showed that Ki-67 organizes the mitotic chromosome periphery and recruits protein phosphatase 1 (PP1) to chromatin at anaphase onset, in a similar manner as RepoMan (Booth et al., 2014). Here we show how Ki-67 and RepoMan form mito...

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Bibliographic Details
Main Authors: Ganesan Senthil Kumar, Ezgi Gokhan, Sofie De Munter, Mathieu Bollen, Paola Vagnarelli, Wolfgang Peti, Rebecca Page
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-08-01
Series:eLife
Subjects:
Ki-67
RepoMan
protein phosphatase 1 (PP1)
cancer
cell cycle
structural biology
Online Access:https://elifesciences.org/articles/16539

Internet

https://elifesciences.org/articles/16539

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