Proteomic Analysis Reveals a Novel Therapeutic Strategy Using Fludarabine for Steroid-Resistant Asthma Exacerbation

Proteomic Analysis Reveals a Novel Therapeutic Strategy Using Fludarabine for Steroid-Resistant Asthma Exacerbation

Virus-induced asthma exacerbation is a health burden worldwide and lacks effective treatment. To better understand the disease pathogenesis and find novel therapeutic targets, we established a mouse model of steroid (dexamethasone (DEX)) resistant asthma exacerbation using ovalbumin (OVA) and influe...

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Bibliographic Details
Main Authors: Xiaoming Liu, Xiang Li, Ling Chen, Alan Chen-Yu Hsu, Kelly L. Asquith, Chi Liu, Karen Laurie, Ian Barr, Paul S. Foster, Ming Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
influenza infection
asthma exacerbation
steroid-resistance
inflammation
proteomics
pathway analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.805558/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.805558/full

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