Inhibition of cerebral ischemia/reperfusion injury-induced apoptosis: nicotiflorin and JAK2/STAT3 pathway

Inhibition of cerebral ischemia/reperfusion injury-induced apoptosis: nicotiflorin and JAK2/STAT3 pathway

Nicotiflorin is a flavonoid extracted from Carthamus tinctorius. Previous studies have shown its cerebral protective effect, but the mechanism is undefined. In this study, we aimed to determine whether nicotiflorin protects against cerebral ischemia/reperfusion injury-induced apoptosis through the J...

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Bibliographic Details
Main Authors: Guang-qiang Hu, Xi Du, Yong-jie Li, Xiao-qing Gao, Bi-qiong Chen, Lu Yu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; brain injury; nicotiflorin; ischemic stroke; cerebral ischemia/reperfusion injury; treatment; cell apoptosis; terminal deoxynucleotidyl transferase dUTP nick end labeling; JAK2/STAT3 pathway; Bcl-2; Bax; caspase-3; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=1;spage=96;epage=102;aulast=Hu

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2017;volume=12;issue=1;spage=96;epage=102;aulast=Hu

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