Picroside Ⅱ alleviates renal fibrosis through YY1-dependent transcriptional inhibition of TGFβ1
Diabetic Nephropathy (DN) has become the leading cause of end-stage renal disease worldwide. Studies have indicated that Transforming Growth Factor beta1 (TGFβ1) is the most potent factor contributing to renal fibrosis, and understanding the exact pathogenic mechanism of renal fibrosis is crucial fo...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-09-01
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Series: | Metabolism Open |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589936824000483 |