Picroside Ⅱ alleviates renal fibrosis through YY1-dependent transcriptional inhibition of TGFβ1

Diabetic Nephropathy (DN) has become the leading cause of end-stage renal disease worldwide. Studies have indicated that Transforming Growth Factor beta1 (TGFβ1) is the most potent factor contributing to renal fibrosis, and understanding the exact pathogenic mechanism of renal fibrosis is crucial fo...

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Bibliographic Details
Main Authors: Xianjing Zhang, Jiarong Zhang, Xiaojun Xu, Suzhen Chen, Fei Gao
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Metabolism Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589936824000483