β1 adrenoceptor antibodies induce myocardial apoptosis via inhibiting PGC-1α-related pathway

β1 adrenoceptor antibodies induce myocardial apoptosis via inhibiting PGC-1α-related pathway

Abstract Background Peripartum cardiomyopathy (PPCM) is life-threatening heart disease. However, the causes and pathogenesis of PPCM remain unclear. Previous studies found that β1 adrenoceptor antibodies (β1AA) had possible involvement in the development of PPCM. In the present study, we determined...

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Bibliographic Details
Main Authors: Linying Shi, Jia Liu, Yuan Zhang, Mulei Chen, Jiamei Liu
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Cardiovascular Disorders
Subjects:
Peripartum cardiomyopathy
Autoantibody against β1 adrenoceptor
Peroxisome proliferator-activated receptor γ coactivator-1α
Vascular endothelial growth factor
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12872-020-01492-3

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http://link.springer.com/article/10.1186/s12872-020-01492-3

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