Hypoxia disruption of vertebrate CNS pathfinding through ephrinB2 Is rescued by magnesium.

The mechanisms of hypoxic injury to the developing human brain are poorly understood, despite being a major cause of chronic neurodevelopmental impairments. Recent work in the invertebrate Caenorhabditis elegans has shown that hypoxia causes discrete axon pathfinding errors in certain interneurons a...

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Bibliographic Details
Main Authors: Tamara J Stevenson, Tony Trinh, Cory Kogelschatz, Esther Fujimoto, Mark E Lush, Tatjana Piotrowski, Cameron J Brimley, Joshua L Bonkowsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3325188?pdf=render