Hypoxia disruption of vertebrate CNS pathfinding through ephrinB2 Is rescued by magnesium.
The mechanisms of hypoxic injury to the developing human brain are poorly understood, despite being a major cause of chronic neurodevelopmental impairments. Recent work in the invertebrate Caenorhabditis elegans has shown that hypoxia causes discrete axon pathfinding errors in certain interneurons a...
Main Authors: | Tamara J Stevenson, Tony Trinh, Cory Kogelschatz, Esther Fujimoto, Mark E Lush, Tatjana Piotrowski, Cameron J Brimley, Joshua L Bonkowsky |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3325188?pdf=render |
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