Long Noncoding RNA CIR Promotes Chondrocyte Extracellular Matrix Degradation in Osteoarthritis by Acting as a Sponge For Mir-27b

Background/Aims: Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degradation. The degradation of the extracellular matrix (ECM) of chondrocyte is closely associated with the destruction of joints in OA patients. lncRNAs are non-coding segments of RNA that pos...

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Bibliographic Details
Main Authors: Yu-Fei Li, Shu-Hua Li, Yong Liu, Ya-Tong Luo
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/480532