A T-cell-related signature for prognostic stratification and immunotherapy response in hepatocellular carcinoma based on transcriptomics and single-cell sequencing

A T-cell-related signature for prognostic stratification and immunotherapy response in hepatocellular carcinoma based on transcriptomics and single-cell sequencing

Abstract Background Hepatocellular carcinoma (HCC) is the fifth most frequently diagnosed malignancy and the third leading cause of cancer death globally. T cells are significantly correlated with the progression, therapy and prognosis of cancer. Limited systematic studies regarding the role of T-ce...

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Bibliographic Details
Main Authors: Xu Chen, Chuang Peng, Yu Chen, Bai Ding, Sulai Liu, Yinghui Song, Yuhang Li, Bo Sun, Ranzhiqiang Yang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Bioinformatics
Subjects:
T-cell marker genes
Single-cell RNA sequencing
Immunotherapy
Hepatocellular carcinoma
Prognostic signature
Online Access:https://doi.org/10.1186/s12859-023-05344-7

Internet

https://doi.org/10.1186/s12859-023-05344-7

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