Ginsenoside Rg5, a potent agonist of Nrf2, inhibits HSV-1 infection-induced neuroinflammation by inhibiting oxidative stress and NF-κB activation

Ginsenoside Rg5, a potent agonist of Nrf2, inhibits HSV-1 infection-induced neuroinflammation by inhibiting oxidative stress and NF-κB activation

Background: Herpes simplex virus type 1 (HSV-1), known to latently infect the host’s trigeminal ganglion, can lead to severe herpes encephalitis or asymptomatic infection, potentially contributing to neurodegenerative diseases like Alzheimer’s. The virus generates reactive oxygen species (ROS) that...

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Bibliographic Details
Main Authors: Buyun Kim, Young Soo Kim, Wei Li, Eun-Bin Kwon, Hwan-Suck Chung, Younghoon Go, Jang-Gi Choi
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Journal of Ginseng Research
Subjects:
Herpes simplex virus type 1
Ginsenoside Rg5
Neuroinflammation
Nuclear factor E2-related factor 2
Infection disease
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845324000071

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http://www.sciencedirect.com/science/article/pii/S1226845324000071

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