Cancer‐associated fibroblast‐derived exosomal microRNA‐20a suppresses the PTEN/PI3K‐AKT pathway to promote the progression and chemoresistance of non‐small cell lung cancer

Cancer‐associated fibroblast‐derived exosomal microRNA‐20a suppresses the PTEN/PI3K‐AKT pathway to promote the progression and chemoresistance of non‐small cell lung cancer

Abstract Background Cancer‐associated fibroblasts (CAFs) contributes to overall tumor progression. In the current survey, we explored the ability of microRNA‐20a (miR‐20a) within these CAF‐derived exosomes to influence non‐small‐cell lung cancer (NSCLC) progression. Materials and methods Normal tiss...

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Bibliographic Details
Main Authors: Lin Shi, Weiliang Zhu, Yuanyuan Huang, Lin Zhuo, Siyun Wang, Shaobing Chen, Bei Zhang, Bin Ke
Format: Article
Language:English
Published: Wiley 2022-07-01
Series:Clinical and Translational Medicine
Subjects:
CAF
exosome
microRNA‐20a
NSCLC
PTEN
Online Access:https://doi.org/10.1002/ctm2.989

Internet

https://doi.org/10.1002/ctm2.989

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