Longitudinal analysis at three oral sites links oral microbiota to clinical outcomes in allogeneic hematopoietic stem-cell transplant

Longitudinal analysis at three oral sites links oral microbiota to clinical outcomes in allogeneic hematopoietic stem-cell transplant

ABSTRACT Allogeneic hematopoietic stem-cell transplant (allo-HSCT) is potentially curative for several hematological disorders. Before stem-cell infusion, recipients undergo a conditioning regimen with chemo/radiotherapy and immunosuppressants, requiring the use of antibiotics to treat and prevent i...

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Bibliographic Details
Main Authors: Vitor Heidrich, Franciele H. Knebel, Julia S. Bruno, Vinícius C. de Molla, Wanessa Miranda-Silva, Paula F. Asprino, Luciana Tucunduva, Vanderson Rocha, Yana Novis, Eduardo R. Fregnani, Celso Arrais-Rodrigues, Anamaria A. Camargo
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:Microbiology Spectrum
Subjects:
oral microbiome
16S rRNA gene sequencing
allogeneic hematopoietic cell transplant
microbiome stability
blooming of bacteria
biomarkers
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02910-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.02910-23

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