Allele-specific genome-wide profiling in human primary erythroblasts reveal replication program organization.

Allele-specific genome-wide profiling in human primary erythroblasts reveal replication program organization.

We have developed a new approach to characterize allele-specific timing of DNA replication genome-wide in human primary basophilic erythroblasts. We show that the two chromosome homologs replicate at the same time in about 88% of the genome and that large structural variants are preferentially assoc...

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Bibliographic Details
Main Authors: Rituparna Mukhopadhyay, Julien Lajugie, Nicolas Fourel, Ari Selzer, Michael Schizas, Boris Bartholdy, Jessica Mar, Chii Mei Lin, Melvenia M Martin, Michael Ryan, Mirit I Aladjem, Eric E Bouhassira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4006724?pdf=render

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http://europepmc.org/articles/PMC4006724?pdf=render

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