Detecting Microsatellite Instability in Endometrial, Colon, and Stomach Cancers Using Targeted NGS

Detecting Microsatellite Instability in Endometrial, Colon, and Stomach Cancers Using Targeted NGS

Purpose: To develop a method for testing the MSI based on targeted NGS. Methods: Based on the results of previous studies, 81 microsatellite loci with high variability in MSI-H tumors were selected, and a method for calculating the MSI score was developed. Using the MSI score, we defined the MSI sta...

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Bibliographic Details
Main Authors: Ulyana Boyarskikh, Andrey Kechin, Evgeniy Khrapov, Mikhail Fedyanin, Grigory Raskin, Marina Mukhina, Elena Kravtsova, Aleksey Tsukanov, Sergey Achkasov, Maksim Filipenko
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
microsatellite instability
endometrial cancers
targeted NGS
Online Access:https://www.mdpi.com/2072-6694/15/20/5065

Internet

https://www.mdpi.com/2072-6694/15/20/5065

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