Genomic insights into the mechanisms of FGFR1 dependency in squamous cell lung cancer

Although subsets of patients with lung squamous cell carcinoma (LSCC) benefit from immunotherapy, there are few effective molecularly targeted treatments for LSCC. Fibroblast growth factor receptor (FGFR) inhibitors provide a therapeutic option for patients with LSCC harboring FGFR aberrations, but...

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Bibliographic Details
Main Authors: Netta Mäkinen, Matthew Meyerson
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-11-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI174171