Three-Dimensional Interaction Homology: Deconstructing Residue–Residue and Residue–Lipid Interactions in Membrane Proteins

A method is described to deconstruct the network of hydropathic interactions within and between a protein’s sidechain and its environment into residue-based three-dimensional maps. These maps encode favorable and unfavorable hydrophobic and polar interactions, in terms of spatial positions for optim...

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Bibliographic Details
Main Author: Glen E. Kellogg
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/12/2838