Gliosarcoma Is Driven by Alterations in PI3K/Akt, RAS/MAPK Pathways and Characterized by Collagen Gene Expression Signature

Gliosarcoma Is Driven by Alterations in PI3K/Akt, RAS/MAPK Pathways and Characterized by Collagen Gene Expression Signature

Gliosarcoma is a very rare brain tumor reported to be a variant of glioblastoma (GBM), IDH-wildtype. While differences in molecular and histological features between gliosarcoma and GBM were reported, detailed information on the genetic background of this tumor is lacking. We intend to fill in this...

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Bibliographic Details
Main Authors: Bartosz Wojtas, Bartlomiej Gielniewski, Kamil Wojnicki, Marta Maleszewska, Shamba S. Mondal, Pawel Nauman, Wieslawa Grajkowska, Rainer Glass, Ulrich Schüller, Christel Herold-Mende, Bozena Kaminska
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
gliosarcoma
glioblastoma
transcriptome
PI3K/Akt
RAS/MAPK
mutation
collagen
Online Access:https://www.mdpi.com/2072-6694/11/3/284

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https://www.mdpi.com/2072-6694/11/3/284

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