Single unpurified breast tumor-initiating cells from multiple mouse models efficiently elicit tumors in immune-competent hosts.

The tumor-initiating cell (TIC) frequency of bulk tumor cell populations is one of the criteria used to distinguish malignancies that follow the cancer stem cell model from those that do not. However, tumor-initiating cell frequencies may be influenced by experimental conditions and the extent to wh...

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Bibliographic Details
Main Authors: Natasza A Kurpios, Adele Girgis-Gabardo, Robin M Hallett, Stephen Rogers, David W Gludish, Lisa Kockeritz, James Woodgett, Robert Cardiff, John A Hassell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608640?pdf=render