High and Low Levels of <i>ABCB1</i> Expression Are Associated with Two Distinct Gene Signatures in Lung Tissue of Pulmonary TB Patients with High Inflammation Activity

High and Low Levels of <i>ABCB1</i> Expression Are Associated with Two Distinct Gene Signatures in Lung Tissue of Pulmonary TB Patients with High Inflammation Activity

P-glycoprotein (encoded by the <i>ABCB1</i> gene) has a dual role in regulating inflammation and reducing chemotherapy efficacy in various diseases, but there are few studies focused on pulmonary TB patients. In this study, our objective was to identify a list of genes that correlate wit...

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Bibliographic Details
Main Authors: Ekaterina N. Pavlova, Larisa N. Lepekha, Ekaterina Yu. Rybalkina, Ruslan V. Tarasov, Ksenia A. Sychevskaya, Elena E. Voronezhskaya, Alexander G. Masyutin, Atadzhan E. Ergeshov, Maria V. Erokhina
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
<i>ABCB1</i>
<i>STAT3</i>
pulmonary tuberculosis
chronic inflammation
signature of gene expressions
Online Access:https://www.mdpi.com/1422-0067/24/19/14839

Internet

https://www.mdpi.com/1422-0067/24/19/14839

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