Indole-3-carbinol in vitro antiviral activity against SARS-Cov-2 virus and in vivo toxicity

Indole-3-carbinol in vitro antiviral activity against SARS-Cov-2 virus and in vivo toxicity

Abstract The effects of indole-3-carbinol (I3C) compound have been described deeply as antitumor drug in multiple cancers. Herein, I3C compound was tested for toxicity and antiviral activity against SARS-CoV-2 infection. Antiviral activity was assessed in vitro in both in VeroE6 cell line and human...

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Bibliographic Details
Main Authors: Federica Centofanti, Tonino Alonzi, Andrea Latini, Paola Spitalieri, Michela Murdocca, Xiaodong Chen, Weibo Cui, Qianwen Shang, Delia Goletti, Yufang Shi, Andrea Duranti, Carlo Tomino, Michela Biancolella, Federica Sangiuolo, Maria Rosaria Capobianchi, Suresh Jain, Giuseppe Novelli, Pier Paolo Pandolfi
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01280-2

Internet

https://doi.org/10.1038/s41420-022-01280-2

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