Phosphodiesterase 5a Signalling in Skeletal Muscle Pathophysiology

Phosphodiesterase 5a Signalling in Skeletal Muscle Pathophysiology

Phosphodiesterase 5A (PDE5A) is involved in cGMP hydrolysis, regulating many physiological processes. Increased activity of PDE5A has been found in several pathological conditions, and the pharmacological inhibition of PDE5 has been demonstrated to have several therapeutic applications. We have iden...

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Bibliographic Details
Main Authors: Valeria De Arcangelis, Luciana De Angelis, Federica Barbagallo, Federica Campolo, Ana Gabriela de Oliveira do Rego, Manuela Pellegrini, Fabio Naro, Mauro Giorgi, Lucia Monaco
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
phosphodiesterases
<i>Pde5a</i> isoforms
muscular disorders
atrophy
Online Access:https://www.mdpi.com/1422-0067/24/1/703

Internet

https://www.mdpi.com/1422-0067/24/1/703

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