Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics

Abstract Delayed diagnosis and misdiagnosis are frequent in people with amyotrophic lateral sclerosis (ALS), the most common form of motor neuron disease (MND). Neurofilament light chain (NFL) and phosphorylated neurofilament heavy chain (pNFH) are elevated in ALS patients. We retrospectively quanti...

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Bibliographic Details
Main Authors: Arvin Behzadi, Fani Pujol-Calderón, Anton E. Tjust, Anna Wuolikainen, Kina Höglund, Karin Forsberg, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Peter Munch Andersen
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01499-6