The inorganic NItrate and eXercise performance in Heart Failure (iNIX-HF) phase II clinical trial: Rationale and study design

The inorganic NItrate and eXercise performance in Heart Failure (iNIX-HF) phase II clinical trial: Rationale and study design

Background: Heart failure (HF) is a debilitating and often fatal disease that affects millions of people worldwide. Diminished nitric oxide synthesis, signaling, and bioavailability are believed to contribute to poor skeletal muscle function and aerobic capacity. The aim of this clinical trial (iNIX...

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Bibliographic Details
Main Authors: Andrew R. Coggan, Lauren K. Park, Susan B. Racette, Victor G. Davila-Roman, Pattie Lenzen, Kathryn Vehe, Peter M. Dore, Kenneth B. Schechtman, Linda R. Peterson
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Contemporary Clinical Trials Communications
Subjects:
Heart failure
Nitric oxide
Dietary nitrate
Peak oxygen consumption
Muscle power
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865423001540

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http://www.sciencedirect.com/science/article/pii/S2451865423001540

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