The Effect of Model Directionality on Cell-Type-Specific Differential DNA Methylation Analysis
Calling differential methylation at a cell-type level from tissue-level bulk data is a fundamental challenge in genomics that has recently received more attention. These studies most often aim at identifying statistical associations rather than causal effects. However, existing methods typically mak...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-01-01
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| Series: | Frontiers in Bioinformatics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fbinf.2021.792605/full |