High-throughput synapse-resolving two-photon fluorescence microendoscopy for deep-brain volumetric imaging in vivo

Optical imaging has become a powerful tool for studying brains in vivo. The opacity of adult brains makes microendoscopy, with an optical probe such as a gradient index (GRIN) lens embedded into brain tissue to provide optical relay, the method of choice for imaging neurons and neural activity in de...

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Bibliographic Details
Main Authors: Guanghan Meng, Yajie Liang, Sarah Sarsfield, Wan-chen Jiang, Rongwen Lu, Joshua Tate Dudman, Yeka Aponte, Na Ji
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/40805