Combined Hepatotoxicity and Toxicity Mechanism of Intermedine and Lycopsamine

Pyrrolizidine alkaloids (PAs) are common constituents of plants and have serious hepatotoxicity. Intermedine (Im) and lycopsamine (La) are two monoesters of PAs that frequently coexist in the PA-containing plants (e.g., <i>comfrey</i> and tea). The present study aimed to explore the comb...

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Bibliographic Details
Main Authors: Ziqi Wang, Liang Qiao, Qinqin Zheng, Haolei Han, Zuguang Li, Xiangchun Zhang, Hongping Chen
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/14/9/633