Response to treatment in Brazilian patients with chronic hepatitis C is associated with a single-nucleotide polymorphism near the interleukin-28B gene

A single-nucleotide polymorphism (SNP) upstream of interleukin (IL)28B was recently identified as an important predictor of the outcome of chronic hepatitis C patients treated with pegylated interferon plus ribavirin (PEG-IFN/RBV). The aim of this study was to investigate the association between the...

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Main Authors: Tarciana Grandi, Cláudia Maria Dornelles da Silva, Karine Medeiros Amaral, Paulo Dornelles Picon, Cintia Costi, Nicole Nascimento da Fré, Marilu Fiegenbaum, Christian Niel, Maria Lucia Rosa Rossetti
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-02-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000100008