Characterization of prevalent tyrosine kinase inhibitors and their challenges in glioblastoma treatment

Glioblastoma multiforme (GBM) is a highly aggressive malignant primary tumor in the central nervous system. Despite extensive efforts in radiotherapy, chemotherapy, and neurosurgery, there remains an inadequate level of improvement in treatment outcomes. The development of large-scale genomic and pr...

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Bibliographic Details
Main Authors: Mahdie Rahban, Sara Joushi, Hamideh Bashiri, Luciano Saso, Vahid Sheibani
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1325214/full