The Evi5 oncogene promotes laryngeal cancer cells proliferation by stabilizing c-Myc protein

Abstract Background The Ecotropic viral integration site 5 (Evi5) is recognized as a potential oncogene and a cell cycle regulator. Evi5 regulates the abundance of Emi1, an inhibitor of the anaphase-promoting complex/cyclosome, to govern mitotic fidelity. Evi5 has been shown to be dysregulated in se...

Full description

Bibliographic Details
Main Authors: Cheng-Gang Mao, Xiao-Chun Zhou, Yi-Dao Jiang, Li-Jia Wan, Ze-Zhang Tao, Jun Guo
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-020-1127-0