The Evi5 oncogene promotes laryngeal cancer cells proliferation by stabilizing c-Myc protein
Abstract Background The Ecotropic viral integration site 5 (Evi5) is recognized as a potential oncogene and a cell cycle regulator. Evi5 regulates the abundance of Emi1, an inhibitor of the anaphase-promoting complex/cyclosome, to govern mitotic fidelity. Evi5 has been shown to be dysregulated in se...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-02-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-020-1127-0 |