ABCG2 polymorphisms and susceptibility to ARV‐associated hepatotoxicity

ABCG2 polymorphisms and susceptibility to ARV‐associated hepatotoxicity

Abstract Background The ABCG2 421C/A polymorphism contributes significantly to the distribution and absorption of antiretroviral (ARV) regimens and is associated with the undesirable side effects of efavirenz. Methods To investigate this, we examined ABCG2 34G/A (rs2231137) and 421C/A (rs2231142) ge...

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Bibliographic Details
Main Authors: HariOm Singh, Kishore Dhotre, Shyamveer, Ranjana Choudhari, Amita Verma, Supriya D. Mahajan, Nemat Ali
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
ABCG2 polymorphism
ARV‐associated hepatotoxicity
genetic susceptibility
haplotypes
HIV patients
Online Access:https://doi.org/10.1002/mgg3.2362

Internet

https://doi.org/10.1002/mgg3.2362

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